People can lower their cholesterol levels by making lasting changes to their diet and lifestyle. Both Nexlizet and Nexletol contain bempedoic acid (in the same strength) as an active drug. Lowering your cholesterol: How long does it take? And don’t throw away the packet that helps keep your medication dry. The NEXLETOL & NEXLIZET Co-Pay Card is not health insurance or a benefit plan. (Bempedoic acid is one of Nexlizet’s active drugs.) Estimated cash price $395.99. HeFH is an inherited condition that causes high cholesterol. Cholesterol occurs naturally in your body. But once you stop taking the drug, your LDL cholesterol may increase again. (LDL cholesterol is also known as “bad” cholesterol.) You should store Nexlizet tablets at room temperature, which is around 68°F to 77°F (20°C to 25°C). This can increase your risk for side effects from Nexlizet.*. They’ll likely reduce your statin dose. How does stress affect cholesterol levels? But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. Bempedoic acid works by reducing the amount of cholesterol made by the liver. The drug can be taken with or without food. But statins work by blocking a different enzyme, called HMG-CoA reductase. Keep Nexlizet tablets in their original container and store them away from light. The Food and Drug Administration (FDA) approves prescription drugs such as Nexlizet to treat certain conditions. This is because it can build up in the arteries and lead to angina (chest pain) or a heart attack. Prior approval is required to ensure the safe, clinically appropriate and cost effective use of Nexletol and Nexlizet while maintaining optimal therapeutic outcomes. You may wonder how Nexlizet compares with other medications that are prescribed for similar uses. But it isn’t known how often this side effect may have occurred in clinical studies of Nexlizet. We comply with the HONcode standard for trustworthy health information -, Drug class: antihyperlipidemic combinations, Here are 10 ways to save money on prescription drugs, FDA Approved Diagnosis - See Program Website for Details. The lowest GoodRx price for the most common version of Nexlizet is around $333.12, 16% off the average retail price of $399.35. Nexlizet may also be used off-label for other conditions. 2. Nexlizet works by decreasing the amount of cholesterol made in your liver. NEXLIZET is contraindicated in patients with a known hypersensitivity to ezetimibe tablets. * Your patients can assess their eligibility and enroll for a Co-Pay Card online at NexCopay.com. More information please phone: 855-699-8814Visit Website. These lists do not include all possible side effects. But if it’s almost time for your next dose, skip your missed dose and take the next dose on your regular schedule. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (‘bad’) cholesterol in certain people. Tell them about all prescription, over-the-counter, and other drugs you take. They can recommend treatments that may help reduce your muscle spasms. Limitations of Use The effect of NEXLIZET on cardiovascular morbidity and mortality has not been … Grapefruit can prevent statins from clearing out of your body. Ann Arbor, MI: Epserion Therapeutics, Inc.; February 2020. Nexlizet comes as a tablet that you swallow. Nexlizet may not be right for you if you have certain medical conditions or other factors affecting your health. Other drugs are available that can treat your condition. Examples of bile acid sequestrants include cholestyramine (Prevalite) and colesevelam (Welchol). No, Nexlizet isn’t a statin. It’s not known if Nexlizet is safe to take during pregnancy. Clinical studies of possible drug interactions with Nexlizet haven’t been done. References 1. This can include setting an alarm on your phone or downloading a reminder app. It’s approved for this use in adults with certain conditions. Lowering "bad" cholesterol may … If you’re interested in this option, check with your doctor and insurance company. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. NEXLIZET Savings, Coupons and Information. Be sure to tell your doctor if you’re taking either of these drugs before you start Nexlizet. You can take the drug at any time of day, but try to take it at the same time each day. (A drug class is a group of drugs that work in a similar way.) Also, tell them about any vitamins, herbs, and supplements you use. Nexletol and Nexlizet will be sold at a wholesale acquisition cost of $10 per day, an Esperion spokesman said, a price the drugmaker said was far below that of PCSK9 meds Repatha from Amgen and Praluent from Sanofi and Regeneron. But having more cholesterol than your body can use may lead to serious problems, such as heart disease. Nexlizet works to lower your cholesterol in two ways: * An enzyme is a protein that speeds up the chemical processes in your body. It also has favorable safety and excellent access at a low cost for patients.” Important: When there is a range of pricing, consumers should normally expect to pay the lower price. In addition to taking Nexlizet, your doctor will probably recommend that you follow a low cholesterol diet. The cost for Nexlizet oral tablet (180 mg-10 mg) is around $8 for a supply of 90 tablets, depending on the pharmacy you visit. If you’d like to notify the FDA about a side effect you’ve had with Nexlizet, you can do so through MedWatch. If you take Nexlizet with one of these statins, your doctor will likely decrease your statin dose. * (For more information, see the “Nexlizet interactions” section above.). It also helps prevent your small intestine from absorbing cholesterol. NEXLIZET is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of LDL-C. Contact program for details. Last medically reviewed on December 12, 2020, There are three types of cholesterol: HDL or good cholesterol, LDL or bad cholesterol, and total cholesterol. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. This means there should be less of a concern about running out of the medication. Nexlizet is approved to help lower a certain type of cholesterol called LDL. Talk with your doctor if you have questions about eating certain foods with Nexlizet. They may have you stop taking the drug until they can find out if you’ve had a tendon rupture. But this side effect could affect any tendon in the body. Symptoms of a severe allergic reaction can include: Call your doctor right away if you have an allergic reaction to Nexlizet, as the reaction could become severe. The patient must also be residing in the US. Increased liver enzymes can be a sign that your liver isn’t working correctly. Nexlizet may cause hyperuricemia (high blood levels of uric acid). Compare your medication cost with and without insurance at checkout. You shouldn’t breastfeed while taking Nexlizet. © 2004-2021 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. (For more information about this interaction, see the “Nexlizet interactions” section above.). Nexlizet is approved for this use in adults with either of the following conditions: * It’s not known if Nexlizet can decrease the risk of heart problems and death related to high cholesterol. Nexlizet is typically taken with statin drugs to help reduce low-density lipoprotein (LDL) cholesterol. Bempedoic acid is one of the active ingredients in Nexlizet. Nexlizet is approved to help reduce low-density lipoprotein (LDL) cholesterol* when used alongside a low cholesterol diet and a statin. Statins are another group of drugs used to treat high cholesterol. What are the common themes of cholesterol-cutting diets? Nexlizet is meant to be used as a long-term treatment. Note: All new enrollment is now done electronically or over the phone. Some cholesterol … (For more information about how the drug is used, see the “Nexlizet uses” section above.). It’s available in one strength: 180 milligrams (mg) of bempedoic acid/10 mg of ezetimibe. * Then, they’ll monitor whether the drug is working for you and whether you experience any side effects.† Your doctor may stop your Nexlizet treatment if it isn’t safe or effective for you. Get started today › Looking up your meds. In clinical studies, adults were given either bempedoic acid or a placebo (a treatment without an active drug). The cost you find on GoodRx.com is what you may pay without insurance. Discount Pricing For Nexlizet 30 180mg-10mg tablet. Other interactions can increase side effects or make them more severe. 2. Step therapy programs are utilized to encourage use of lower cost alternatives for certain therapeutic classes. (Tendons are tissues that connect muscles to bones.). You should take Nexlizet according to your doctor’s or healthcare provider’s instructions. This helps prevent others, including children and pets, from taking the drug by accident. Hypersensitivity reactions including anaphylaxis, angioedema, rash, and urticaria have been reported with ezetimibe. If it does pass into breast milk, the drug may cause serious side effects in a child who is breastfed. These factors include: Symptoms of a tendon rupture include joint pain, swelling, or bruising. If you drink alcohol, talk with your doctor about how much is safe for you to drink while taking Nexlizet. Nexlizet can interact with bile acid sequestrants, which are a group of drugs used to treat high cholesterol. A kitchen timer can also work. For those that need NEXLIZET or NEXLETOL, Esperion’s mission is to considerably reduce cost as a burden for patients as they strive to achieve their long-term LDL-C goals. This article provides several useful tips on medication disposal. Learn how pricing works › Have your meds delivered. A generic drug is an exact copy of the active drug in a brand-name medication. For instance, some interactions can interfere with how well a drug works. A tendon rupture (a torn tendon) can happen while taking Nexlizet. It isn’t known whether Nexlizet is safe to use during pregnancy. There are no known interactions between Nexlizet and alcohol. Talk with your doctor before starting Nexlizet if you’re pregnant or planning a pregnancy. Full prescribing information may be found here. Related policies Juxtapid, Praluent, Repatha Policy This policy statement applies to clinical review performed for pre-service (Prior Approval, Precertification, Advanced Benefit … (Ezetimibe is one of the active drugs in Nexlizet.) You can take Nexlizet with or without food. The recommended dosage for this purpose is one tablet once per day. If they do, they may prescribe Nexlizet so that you can take bempedoic acid and ezetimibe together in a single pill. No, Nexlizet won’t cure high levels of low-density lipoprotein (LDL) cholesterol. Find patient medical information for Nexlizet oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Vyepti Approved for Migraine Prevention The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. All rights reserved. (See “Does Nexlizet have to be used with a statin?” just above for more information.). Here are answers to some frequently asked questions about Nexlizet. Doing so can help lower your cholesterol levels, which can help decrease your risk for heart disease. * If you take Nexlizet while also taking a bile acid sequestrant, Nexlizet should be taken at least 2 hours before or 4 hours after the bile acid sequestrant. If you have a tendon rupture while taking Nexlizet, your doctor will likely change your treatment. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This medication should be used along with a statin drug and a low cholesterol diet. Stress can trigger changes in hormone levels…, In this article, we look at a variety of lifestyle changes and natural supplements that help lower cholesterol levels and reduce the risk of heart…. Here’s some detail on certain side effects this drug may cause. Before starting Nexlizet, if you’re taking a statin, be sure to tell your doctor which one you take. It’s not known if the drug can pass into breast milk while breastfeeding. In the study, LDL (“bad”) cholesterol levels decreased by an average of: LDL cholesterol increased by an average of 2% in people who used a placebo. Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Taking ezetimibe and bempedoic acid together can help reduce LDL cholesterol even more than taking bempedoic acid by itself. Call 911 or your local emergency number if your symptoms feel life threatening or you think you’re having a medical emergency. You save $69.09. Nexlizet comes as a tablet that you swallow. The Food and Drug Administration (FDA) has approved Nexlizet to help reduce low-density lipoprotein (LDL) cholesterol. Using this service may help lower the drug’s cost and allow you to get your medication without leaving home. So, if you take Nexlizet and have a history of heavy alcohol use, you may have a higher risk for this side effect. Mild side effects* of Nexlizet can include: Most of these side effects may go away within a few days or a couple of weeks. July 2020: Surpassed NEXLETOL and NEXLIZET one-year managed care coverage goals, with over 80% commercial coverage and over 50% Medicare Part D coverage with preferred brand formulary status less than four months after initial launch. Some studies suggest it does, although the link is not clear. | BEMPEDOIC ACID; EZETIMIBE (BEM pe DOE ik AS id; ez ET i mibe) is used to lower the level of cholesterol in the blood. Ezetimibe belongs to a group of drugs called cholesterol absorption inhibitors. Select one or more newsletters to continue. bempedoic acid/ezetimibe. This program provides financial assistance to eligible individuals to cover coinsurance, copayments, healthcare premiums and deductibles for certain treatments. Bempedoic acid is one of the active ingredients in Nexlizet. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office. Off-label drug use is when an FDA-approved drug is used for a purpose other than what it’s approved for. Or they may recommend a treatment option other than Nexlizet. Certain genetic (inherited) conditions, such as HeFH, can cause high cholesterol. Don’t take extra doses to make up for your missed dose. Nexletol [package insert]. It’s available in one strength: 180 milligrams (mg) of bempedoic acid/10 mg of ezetimibe. Methylprednisolone (Medrol) is an example of a corticosteroid. Some drugs that are used to lower cholesterol can also decrease the risk of heart problems and death related to high cholesterol. If you’re taking cyclosporine, talk with your doctor about whether it’s safe for you to take Nexlizet. Nexlizet is available only as a brand-name medication. When you get Nexlizet from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Simvastatin and pravastatin can cause muscle pain and muscle weakness. Nexletol [package insert]. Talk with your doctor if you have questions about breastfeeding while taking Nexlizet. Hyperuricemia … Examples of bile acid sequestrants include cholestyramine (Prevalite) and colesevelam (Welchol). If you have questions about how Nexlizet and Nexletol are alike and different, talk with your doctor. Both Nexlizet and Nexletol are typically taken once per day, with or without with food. Read this article to find out the…. This can raise your statin levels and increase your risk for side effects. In 2020, the Food and Drug Administration (FDA) approved Nexlizet to help reduce LDL cholesterol in adults. See this article to learn more about how grapefruit may interact with medications. HeFH is an inherited condition that causes high cholesterol. Nexlizet contains two active drugs: bempedoic acid and ezetimibe. It is used with other cholesterol -lowering drugs. Nexlizet may be available through a mail-order pharmacy. Eating a lot of high cholesterol foods or not getting enough exercise can also raise cholesterol levels. Nexlizet is a brand-name prescription drug. Some Medicare plans may help cover the cost of mail-order medications. Your Discount Pricing for Nexlizet 30 180mg-10mg tablet. This is because it can build up in the arteries and lead to angina (chest pain) or a heart attack. In the Post-Donut Hole (also called Catastrophic Coverage) stage, Medicare will cover most of your drug costs. Of adults taking bempedoic acid (one of the active ingredients in Nexlizet) or a placebo in clinical studies: The Achilles, bicep, and shoulder tendons were most commonly affected in these clinical studies. Generic Name: bempedoic acid / ezetimibe. But you likely won’t be able to feel Nexlizet decreasing your cholesterol. Nexlizet can raise the levels of these statins in your blood. In this article learn about the vegan diet, the Mediterranean diet, and the TLC diet. The following information describes dosages that are commonly used or recommended. The free Drugs.com Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions. Nexlizet contains two active drugs: bempedoic acid and ezetimibe. Both drugs were approved for patients who have reached their maximum statin tolerance, the company said. You should store Nexlizet tablets with this packet inside the container. Warnings and Precautions: Hyperuricemia: Bempedoic acid, a component of NEXLETOL and NEXLIZET, may increase blood uric acid levels. So, using Nexlizet with medications in the fibrate drug class can increase your risk for gallstones even more. If you need financial support to pay for Nexlizet, or if you need help understanding your insurance coverage, help is available. The results showed that: Hyperuricemia usually occurred within the first 4 weeks of starting bempedoic acid or a placebo. † For more information on this side effect, see “Side effect details” below. Sharing this information can help you avoid potential interactions. Some may be a better fit for you than others. Certain genetic (inherited) conditions, such as heterozygous familial hypercholesterolemia (HeFH), can cause high cholesterol. Before approving coverage for Nexlizet, your insurance company may require you to get prior authorization. Keep in mind that you may be able to get a 90-day supply of Nexlizet. LDL cholesterol is sometimes called “bad” cholesterol. Nexlizet. Here are 10 ways to save money on prescription drugs, Crestor, Lipitor, ezetimibe, Zetia, Nexletol, atorvastatin, simvastatin, rosuvastatin. The expiration date helps guarantee that the medication is effective during this time. event date: event description: 2018-10-09: new application entered in tram: 2018-10-16: new application office supplied data entered in tram: 2019-01-16: assigned to examiner For those that need NEXLIZET or NEXLETOL, Esperion’s mission is to considerably reduce cost as a burden for patients as they strive to achieve their long-term LDL-C goals. Warning. There are several ways to learn about NEXLIZET based on your preference. But clinical studies haven’t shown any negative effects of Nexlizet on the kidneys. If you’re interested in finding an alternative to Nexlizet, talk with your doctor. Don’t use more Nexlizet than your doctor recommends. If you take Nexlizet and a bile acid sequestrant, wait at least 2 hours before or 4 hours after taking the bile acid sequestrant to take Nexlizet. If you have questions about taking Nexlizet with statin drugs, talk with your doctor. Natural remedies for high cholesterol levels, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, by decreasing the amount of cholesterol your, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, 3.6% of people who took bempedoic acid had muscle spasms, 2.3% of people who took a placebo had muscle spasms, 3.5% of people who took bempedoic acid had high blood levels of uric acid, 1.1% of people who took a placebo had high blood levels of uric acid, 1.5% of people who took bempedoic acid had gout, 0.4% of people who took a placebo had gout, 11.2% of people who had a history of gout and were taking bempedoic acid, 1.7% of people who had a history of gout and were taking a placebo, 1% of people who didn’t have a history of gout and were taking bempedoic acid, 0.3% of people who didn’t have a history of gout and were taking a placebo, 0.5% had a tendon rupture while taking bempedoic acid, 0% had a tendon rupture while taking a placebo, Bempedoic acid decreases the amount of cholesterol your. If you’re prescribed these drugs after you’ve started Nexlizet, tell your doctor that as well. Examples of statins include atorvastatin (Lipitor) and rosuvastatin (Crestor). So, your risk for these muscle side effects may increase if you take Nexlizet with either of these statins. This drug should be used along with a low cholesterol diet and a statin drug. Nexlizet has been found effective in helping reduce LDL cholesterol in adults. But Nexlizet may interact with two specific statins: simvastatin (Zocor) and pravastatin (Pravachol). However, due to stock shortages and other unknown variables we cannot provide any guarantee. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If you have questions about using Nexlizet with other cholesterol-lowering drugs, talk with your doctor or pharmacist. Below are examples of medications that can interact with Nexlizet. In clinical studies, bempedoic acid was shown to increase levels of liver enzymes. There aren’t any foods that have been specifically reported to interact with Nexlizet. Prior approval is required to ensure the safe, clinically appropriate and cost effective use of Nexletol and Nexlizet while maintaining optimal therapeutic outcomes. Nexlizet starts working right away to decrease your LDL cholesterol. Also, for those who are eligible for health insurance, but cannot afford the insurance premium, the foundation may be able to help by paying some or all of the medical portion of insurance premiums. Estimated cash price $410.69. For more information about taking Nexlizet during pregnancy, see the “Nexlizet and pregnancy” section above. If you’re not sure if you’ll need to get prior authorization for Nexlizet, contact your insurance company. Generics usually cost less than brand-name drugs. Eligible patients with commercial prescription drug insurance coverage for NEXLETOL or NEXLIZET may pay as little as $10 per fill for up to a 3-month supply. Nexlizet with simvastatin > 20 mg or pravastatin >40 mg (1-2). For information about the effectiveness of Nexlizet, see the “Nexlizet uses” section below. Launch is planned for March 30, 2020, at a wholesale acquisition cost of about $3,650 per year of therapy. The safety and effectiveness of Nexletol and Nexlizet in pediatric patients less than 18 years of age have not been established (1-2). But the use of Nexlizet with fibrates other than fenofibrate isn’t recommended. It’s important to note that there are limitations to using Nexlizet with certain cholesterol-lowering drugs. * Statins are a group of drugs used to treat high cholesterol. The results showed that: Some people in these clinical studies stopped taking their treatment because of bothersome muscle spasms. More information please phone: 800-675-8416 Visit Website, More information please phone: 866-316-7263 Visit Website, Looking to reduce costs at the pharmacy counter? For more information, see the “Nexlizet interactions” section above. They’ll determine the best dosage to fit your needs. *Patients must have health insurance and their insurance must cover the qualifying medication for which they seek assistance. If you have questions about using Nexlizet with fibrate drugs, talk with your doctor. For some drugs, doing so may lead to unwanted side effects or overdose. Call for most recent medications as the list is subject to change and the medication for which you are seeking assistance must treat the disease directly. Access Coupon $333.89. But there are limitations to using Nexlizet with certain cholesterol-lowering drugs. Eating too many high cholesterol foods or not getting enough exercise can also raise cholesterol levels. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. It’s FDA-approved to help reduce low-density lipoprotein (LDL) cholesterol,* also known as “bad” cholesterol. Learn about side effects, costs, and more. See Terms and Conditions. A generic drug is an exact copy of the active drug in a brand-name medication. Nexlizet Co-Pay Card: Eligible commercially insured patients may pay as little as $10 per fill for up to a 3-month supply; for additional information contact the program at 855-699-8814. Nexletol and Nexlizet in pediatric patients less than 18 years of age have not been established (1-2). But Nexletol also contains another active drug, ezetimibe. Esperion Therapeutics, Inc., the manufacturer of Nexlizet, offers a Co-Pay Card that may help lower the amount you pay for the drug. To help make sure that you don’t miss a dose, try using a medication reminder. Bempedoic acid belongs to a group of drugs called adenosine triphosphate-citrate lyase inhibitors. If you have questions about using Nexlizet with other drugs, talk with your doctor or pharmacist. Serious side effects from Nexlizet aren’t common, but they can occur. For more information, read about generic Nexlizet availability. * To learn about the possible side effects of Nexlizet, see the “Nexlizet side effects” section above. For those that need NEXLIZET or NEXLETOL, Esperion’s mission is to considerably reduce cost as a burden for patients as they strive to achieve their long-term LDL-C goals. Talk with your doctor or pharmacist if you have any questions about taking a statin with Nexlizet. 5-min read. * For this purpose, these drugs can be used in adults with either of the following conditions: These drugs should be used along with a low cholesterol diet and a statin drug. Nexlizet is typically used with statin drugs to help reduce LDL cholesterol. Call your doctor right away if you have serious side effects. Bile acid sequestrants can attach to ezetimibe, one of the active drugs in Nexlizet. Certain statins may interact with Nexlizet, however. It’s used in combination with a low cholesterol diet and a statin drug. Nexlizet is available as a brand name drug only, a generic version is not yet available. The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use. You should swallow the tablets whole. If you miss a dose of Nexlizet, take it as soon as you remember. Applies to bempedoic acid/ezetimibe: oral tablet. Both Nexlizet and statins work by preventing your liver from making new cholesterol. Nexlizet can interact with several other medications. For more information, see the “Nexlizet interactions” section above. Some people may experience muscle spasms while taking Nexlizet. Nexlizet contains two active drugs: bempedoic acid and ezetimibe. Generics tend to cost less than brand-name drugs. Nexlizet is approved to help reduce LDL cholesterol in adults with heart disease or heterozygous familial hypercholesterolemia (HeFH). “I anticipate that NEXLIZET will become a go-to option after statins because it provides double the LDL-C lowering efficacy of ezetimibe, without the need for titration.
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